By Bruno Pinamonti, Gianfranco Sinagra
This publication describes the function of easy and complex imaging concepts within the prognosis of alternative forms of cardiomyopathy, together with dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic correct ventricular cardiomyopathy and infiltrative/storage cardiomyopathies. whereas the focus is on echocardiography, the purposes of cardiac magnetic resonance imaging and computed tomography also are defined. all through, a clinically orientated strategy is hired: unique consciousness is paid to differential analysis and diverse fine quality pictures depict the most good points of a number of the sorts of cardiomyopathy. attention can also be given to the genetics of cardiomyopathies, with research of genotype-phenotype relationships. eventually, the aptitude worth of imaging in prognostic overview and in guiding remedy is described.
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3 Laboratory findings that should raise the suspicion of specific cardiac features High serum creatine kinase (CK) HCM DCM RCM Proteinuria with/without low glomerular filtration rate High transaminase HCM RCM High transferrin saturation/ hyperferritinemia Lactic acidosis DCM RCM Myoglobinuria Leukocytopenia HCM HCM DCM HCM DCM HCM DCM Mitochondrial diseases Glycogenosis Danon disease Dystrophinopathies Sarcoglycanopathies Zaspopathies (LDB3 gene) Laminopathies Myotonic dystrophy FKTN mutations Desminopathies Myofibrillar myopathies Anderson–Fabry disease Amyloidosis Mitochondrial diseases Glycogenosis Danon disease Hemochromatosis Mitochondrial diseases Mitochondrial diseases Mitochondrial diseases (TAZ gene/Barth syndrome) HCM hypertrophic cardiomyopathy, DCM dilated cardiomyopathy, RCM restrictive cardiomyopathy, ARVC arrhythmogenic right ventricular cardiomyopathy, TTR transthyretin protein, LEOPARD syndrome lentigines, echocardiograph conduction abnormalities, ocular hypertelorism, pulmonary stenosis, abnormal genitalia, retardation of growth, and sensorineural deafness, FKTN fukutin, TAZ tafazzin 20 F.
1093/europace/eur245 31. Pettersen MD (2014) Cardiomyopathies encountered commonly in the teenage years and their presentation. Pediatr Clin North Am 61(1):173–186. 017 24 F. Brun et al. 32. Rapezzi C, Arbustini E, Caforio AL, Charron P, Gimeno-Blanes J, Helio T, Linhart A, Mogensen J, Pinto Y, Ristic A, Seggewiss H, Sinagra G, Tavazzi L, Elliott PM (2013) Diagnostic work-up in cardiomyopathies: bridging the gap between clinical phenotypes and final diagnosis. A position statement from the ESC Working Group on Myocardial and Pericardial Diseases.
05 between second and third decades f P value computed only between second and third decades g Kruskal–Wallis p value 38 M. Merlo et al. 2 Major and minor criteria for diagnosing DCM Major criteria 1 LVEF 45 % (>2 SD) and/or FS <25 % (>2 SD), as ascertained by echocardiography, radionuclide scanning or angiography 2 LVEDD >117 % of the predicted value corrected for age and body surface area, which corresponds to 2 SD of the predicted normal limit +5 % Minor criteria 1 Unexplained supraventricular (atrial fibrillation or sustained arrhythmias) or ventricular arrhythmias, frequent (>1,000 .