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By Donald R. Korb, Jennifer Craig, Michael Doughty, Jean-Pierre Guillon, George Smith and Alan Tomlinson (Auth.)

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It also prevents contamination of the tear film by skin lipids. This is important since skin lipids differ in composition from tear film lipids and have the potential to destabilize the lipid film (McDonald, 1968). Finally, the lipid forms a barrier which prevents tears from overspilling onto the eyelid (Norn, 1966). Composition The lipid layer comprises polar and non-polar lipids. The primary constituents are mixed wax esters and sterol esters. These make up around 90 per cent of the total lipid.

1985) Innervation of the conjunctiva. Trans. Ophthalmol. Soc. UK, 104, 390–395. Sapse, A. , Stone, W. Jr. and Sercarz, E. E. (1969) Proteins in human tears. I. Immunoelectrophoretic patterns. Arch. , 81, 815–819. Schoenwald, R. , Wurster, D. E. and Barfknecht, C. F. (1998) The role of tear proteins in tear film stability in the dry eye patient and in the rabbit. Adv. Exp. Med. , 438, 391–400. Seal, D. , McGill, J. , Mackie, I. A. et al. (1986) Bacteriology and tear protein profiles of the dry eye.

J. , 10, 984–992. 46 ᭿ THE TEAR FILM Fullard, R. J. and Carney, L. G. (1984) Diurnal variation in human tear enzymes. Exp. , 38, 15–26. Fullard, R. J. and Carney, L. G. (1985) Human tear enzyme changes as indicators of the corneal response to anterior hypoxia. , 63, 678–683. Fullard, R. J. and Carney, L. G. (1986) Use of tear enzyme activities to assess the corneal response to contact lens wear. , 64, 216–220. Fullard, R. J. and Kissner, D. M. (1991) Purification of the isoforms of tear specific prealbumin.

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