Download Clinical Rounds in Endocrinology: Volume I - Adult by Anil Bhansali, Yashpal Gogate PDF

By Anil Bhansali, Yashpal Gogate

This ebook covers attention-grabbing and but frequently tough situations between grownup sufferers in a special Question-Answer structure. Simulating the bed-side case discussions through the ward rounds, one query logically ends up in one other query thereby producing interest and selling evidence-based drugs. Taking the readers during the whole spectrum ranging from etiology and pathophysiology to scientific presentation to administration rules, each one query addresses one key point of the affliction. defined in an easy and lucid narrative, this e-book guarantees sound conceptual figuring out whereas protecting every one subject comprehensively. This quantity covers vital subject matters reminiscent of acromegaly, Cushing syndrome, osteoporosis, hypercalcemia, pheochromocytoma, hyperaldosteronism, thyroid problems and diabetes in grownup sufferers. those instances aren't simply obvious through endocrinologists, yet also are controlled by way of internists, orthopedic surgeons, obstetricians and gynecologists. much less universal issues comparable to adrenal problems and androgen extra have additionally been lined.

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Extra resources for Clinical Rounds in Endocrinology: Volume I - Adult Endocrinology

Sample text

Jameson JL, De Groot LJ. Endocrinology: adult and pediatric. Philadelphia: Elsevier Health Sciences; 2010. 2. Katznelson L, Atkinson JL, Cook DM, Ezzat SZ, Hamrahian AH, Miller KK. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly-2011 update. Endocr Pract. 2011;17:1–44. 3. Longo D, Fauci A, Kasper D, Hauser S, Jameson J, Loscalzo J. Harrison’s principles of internal medicine. 18th ed. New York: McGraw Hill Professional; 2012.

However, it is recommended to monitor tumor size by MRI biannually for a year and, if the tumor size is stable, then annually. Pegvisomant should be avoided in patients with large tumors abutting the optic chiasm or any other vital structures. 2 Acromegaly: Diagnosis and Treatment 35 44. What is the advantage of combination of somatostatin receptor ligands with pegvisomant? Combination of somatostatin receptor ligand and pegvisomant has the advantage of effective control of GH and IGF1 levels, decreased incidence of dysglycemia, lesser requirement of pegvisomant dose, and reduction in the risk of increase in tumor size.

Increase in size of tumor may occur in 3–5% of patients; however, it is not clear whether it is due to the natural history of the tumor or due to the decreased feedback effect of IGF1 on somatotropinoma. However, it is recommended to monitor tumor size by MRI biannually for a year and, if the tumor size is stable, then annually. Pegvisomant should be avoided in patients with large tumors abutting the optic chiasm or any other vital structures. 2 Acromegaly: Diagnosis and Treatment 35 44. What is the advantage of combination of somatostatin receptor ligands with pegvisomant?

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