Download Biomedical Platforms: Realigning the Normal and the by Peter Keating, Alberto Cambrosio PDF

By Peter Keating, Alberto Cambrosio

Since the top of global warfare II, biology and drugs have merged in remarkably effective methods. during this publication Peter Keating and Alberto Cambrosio examine the transformation of medication into biomedicine and its outcomes, starting from the recasting of clinic structure to the redefinition of the human physique, disorder, and healing practices. to explain this new alignment among the traditional and the pathological, the authors introduce the idea of the biomedical platform. outlined as a particular configuration of tools, contributors, and courses, biomedical systems generate workouts, entities, and actions, held jointly by way of usual reagents and protocols. organic entities resembling phone floor markers, oncogenes, and DNA profiles now exist as either basic organic parts of the organism and as pathological symptoms -- that's, as biomedical elements. The suggestion of a biomedical platform permits researchers attracted to the advance of up to date drugs to explain occasions and approaches missed by means of different approaches.The authors specialise in a particular biomedical platform often called immunophenotyping. They describe its emergence as an experimental approach with roots in biology (immunology) and pathology (oncology). They recount how this experimental process used to be remodeled right into a biomedical platform first and foremost for the prognosis of leukemia and as a result for different ailments similar to AIDS. via this example learn, they convey biomedical platform is the bench upon which conventions about the organic or basic are attached with conventions about the scientific or pathological. They detect that new structures are frequently aligned with present ones and built-in into an increasing set of clinical-biological strategies.

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Extra info for Biomedical Platforms: Realigning the Normal and the Pathological in Late-Twentieth-Century Medicine (Inside Technology)

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01% malignant cells. 35 After noting that the question had been “addressed (although not totally resolved)” by a recently published consensus statement (we discuss the production of consensus recommendations in chapter 9), a second contributor, while averring that “immunophenotypic analysis of bone marrow with morphologically obvious lymphoma . . is generally considered redundant,” nonetheless conceded that Detection of minimal disease does at times create a therapeutic dilemma. . However, it does provide what most consider useful, objective information and can increase the rate of detection by another 10–20% .

59 We are aware that the turf struggle between pathologists and medical biologists could be used to argue that, contrary to what we maintained in chapter 1, professional segments are the key to an understanding of the situation. We would disagree. The professional categories in this case are the epiphenomena. Medical biologists are defined by the hospital platform. Pathologists, in turn, had to choose whether or not to embark. In other words, the professional issue is derivative of the problems imposed by the platform.

But such divisions would be at odds with the participants’ views. The researchers and clinicians who posted the conflicting messages are clearly engaged in what they perceive as the same kind of activity and thus, in some sense, belong to a single group. In other words, taken on their own terms, the actors we quoted inhabit a single world in addition to a single electronic discussion forum. This common world also houses many platforms, whose role in that world, judging from the debate we have just summarized, is far from marginal.

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